Temperature considerations during irreversible electroporation
نویسندگان
چکیده
a School of Biomedical Engineering and Sciences, Virginia Tech-Wake Forest University, Blacksburg, VA 24061, USA Department of Bioengineering, Department of Mechanical Engineering and Graduate Program in Biophysics, University of California at Berkeley, Berkeley, CA 94720, USA Center for Bioengineering in the Service of Humanity and Society, School of Computer Science and Engineering, Hebrew University of Jerusalem, Givat Ram, Jerusalem 91904, Israel
منابع مشابه
Tissue heating during tumor ablation with irreversible electroporation
Exposing biological cells to sufficiently strong external electric fields causes electroporation of cell membranes, i.e. occurrence of transient or permanent permeable pathways between the interior and exterior of the cell. Electroporation can be used to introduce various molecules into cells (reversible electroporation) or to kill cells (irreversible electroporation), which can in turn be used...
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Irreversible electroporation (IRE) has been shown to be an effective method of killing cells locally. In contrast to radiofrequency ablation, the mechanism by which cells are thought to die via IRE is the creation of pores in cell membranes, without substantial increase in tissue temperature. To determine the degree to which cell death is non-thermal, we evaluated IRE in porcine hepatocytes in ...
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* Correspondence: Damijan. [email protected] University of Ljubljana, Faculty of Electrical Engineering, Ljubljana, 1000, Slovenia When a cell is exposed to a sufficiently intense electric field (for a sufficient duration), local defects in the cell membrane appear and become permeable to molecules that otherwise cannot pass through it. This phenomenon is commonly known as electroporation ...
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تاریخ انتشار 2008